Reaktion #50987

Reaktionsgleichung

3-benzyloxyaniline

benzoyl chloride

→

compound 25

phenyl-N-[3-(phenylmethoxy)phenyl]carboxamide

Lösungsmittel

CH2Cl2

water

Reaktionsbedingungen

Aufarbeitung

1. 1
   Filtrationthe resulting solid was collected by vacuum filtration
2. 2
   Sonstigeto air dry

Vorschrift

To a solution of 3-benzyloxyaniline 23 (1.0 g, 5.0 mmol) and TEA (0.74 mL, 5.3 mmol) in CH2Cl2 was added benzoyl chloride (0.61 mL, 5.26 mmol) dropwise and the mixture was allowed to stir overnight. The reaction mixture was diluted with water and the resulting solid was collected by vacuum filtration. The solid was allowed to air dry, to yield compound 25 as a white solid. Synthesis of phenyl{[(3-phenylmethoxy)phenyl]amino}methane-1-thione (26):

Quelle