Reaktion #50745

ord-1175029bb47c455caecd1dd090779881

Reaktionsgleichung

O=C(O)CC(=O)O
malonic acid
CC(=O)O[N+](=O)[O-]
acetyl nitrate
→
O=C(O)C(C(=O)O)[N+](=O)[O-]
nitromalonic acid

Edukte

O=C(O)CC(=O)O
malonic acid
CC(=O)O[N+](=O)[O-]
acetyl nitrate

Reagenzien

Keine

Lösungsmittel

CC(=O)O.CC(=O)OC(C)=O
acetic acid acetic anhydride

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

Nitration of malonic acid with acetyl nitrate in acetic acid/acetic anhydride was conducted to obtain nitromalonic acid. To the nitromalonic acid is added urea to obtain a condensation reaction mixture which is refluxed to form dilituric acid in situ. Various salts are separately prepared from the dilituric acid in situ using as cation sources potassium chloride, ammonia, and guanidinium chloride. The potassium diliturate salt, ammonium diliturate, guanidinium diliturate salts are each recovered and isolated by filtration.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US05428165uspto-grants-1995_06