Reaktion #50701

Reaktionsgleichung

2-amino-5-methyl-benzoic acid

hydrogen

→

2-Carboxy-4-methylcyclohexan-1-yl-amine

Lösungsmittel

tetrahydrofuran

Reaktionsbedingungen

Aufarbeitung

1. 1
   TemperaturAfter cooling
2. 2
   Sonstigeevaporation, 30 g o f 2-carboxy-4-methyl-cyclohexan-1-yl -amine
3. 3
   Sonstigeare obtained as a pale oil

Vorschrift

50 g (0.33 mol) of 2-amino-5-methyl-benzoic acid, dissolved in 100 ml of tetrahydrofuran, are hydrogenated for 14 hours at 200° C. and 200 bar hydrogen in the presence of 5 g of ruthenium/charcoal. After cooling and evaporation, 30 g o f 2-carboxy-4-methyl-cyclohexan-1-yl -amine are obtained as a pale oil.

Quelle