Reaktion #5068

Reaktionsgleichung

potassium carbonate

bromoacetonitrile

amine hydrochloride

4-[(1,4-Benzodioxan-5-yl)]-1,2,3,6-tetrahydropyridine hydrochloride

→

[4-(1,4-Benzodioxan-5-yl)-1,2,3,6-tetrahydropyrid-1-yl]acetonitrile

Lösungsmittel

acetone

acetone

Reaktionsbedingungen

Vorschrift

2.5 g of potassium carbonate and, dropwise, a solution of 1.08 g of bromoacetonitrile in 10 ml of acetone are added to a solution of 1.9 g of the amine hydrochloride obtained in Stage B in 40 ml of acetone.

Quelle