Reaktion #5066

ord-8e041e10770c49b4839e80c7837e0520

Reaktionsgleichung

COc1ccc2c(c1)C(C1CCN(C)CC1)=CCC2
product
COc1ccc2c(c1)C(C1CCN(C)CC1)=CCC2
4-(3,4-Dihydro-7-methoxynaphth-1-yl)-1-methylpiperidine
O=C1C(=O)C(Cl)=C(Cl)C(Cl)=C1Cl
tetrachloro-1,2-benzoquinone
→
COc1ccc2cccc(C3CCN(C)CC3)c2c1
4-(7-Methoxynaphth-1-yl)-1-methylpiperidine

Edukte

COc1ccc2c(c1)C(C1CCN(C)CC1)=CCC2
product
COc1ccc2c(c1)C(C1CCN(C)CC1)=CCC2
4-(3,4-Dihydro-7-methoxynaphth-1-yl)-1-methylpiperidine
O=C1C(=O)C(Cl)=C(Cl)C(Cl)=C1Cl
tetrachloro-1,2-benzoquinone

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Aufarbeitung

  1. 1
    Temperaturis refluxed for 30 hours

Vorschrift

A mixture of 11.5 g of the product from Example 15 and 23.1 g of tetrachloro-1,2-benzoquinone in solution in 600 ml of anhydrous ethyl acohol is refluxed for 30 hours.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US05242933uspto-grants-1993_09