Reaktion #50637

Reaktionsgleichung

potassium hydrogencarbonate

2,3-dihydro-8-hydroxy-7-methoxy-cyclopenta[c][1]benzopyran-4(1H)-one

3-chloro-1-propanol

→

2,3-dihydro-8-(3-hydroxypropoxy)-7-methoxy-cyclopenta[c][1]benzopyran-4(1H)-one

Ausbeute 58.0%

Lösungsmittel

isopropanol

Reaktionsbedingungen

Vorschrift

Method J (but using potassium hydrogencarbonate); Starting materials: 2,3-dihydro-8-hydroxy-7-methoxy-cyclopenta[c][1]benzopyran-4(1H)-one (example 109) and 3-chloro-1-propanol; yield 58%; fusion point 213°-215° C. (from isopropanol).

Quelle