Reaktion #50554

Reaktionsgleichung

4,5-Dihydro-1-phenyl-1H-pyrazol-3-amine

4-amino-2,6-dimethylphenyl acetate

toluene-4-sulfonic acid

→

title product

Ausbeute 46.7%

4-[4,5-Dihydro-1-phenyl-1H-pyrazol-3-yl]amino-2,6-di methylphenyl acetate

Ausbeute 46.7%

Lösungsmittel

toluene

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeEvaporation and chromatography (silica, dichloromethane/ethyl acetate [95:5]) of the residue

Vorschrift

4,5-Dihydro-1-phenyl-1H-pyrazol-3-amine (0.16 g), 4-amino-2,6-dimethylphenyl acetate (0.2 g), and toluene-4-sulfonic acid (0.02 g) were refluxed in toluene under nitrogen for 8 hours. Evaporation and chromatography (silica, dichloromethane/ethyl acetate [95:5]) of the residue gave the title product (0.15 g), as a solid.

Quelle