Reaktion #50368

ord-aa165162a2e042ea8030a1f87d6b5d99

Reaktionsgleichung

[Na+].[OH-]
sodium hydroxide
OCC1CO1
glycidol
O=C(O)C=Cc1ccc(O)cc1
p-hydroxy cinnamic acid
Cl
hydrochloric acid
→
O=C(O)C=Cc1ccccc1
cinnamic acid

Edukte

[Na+].[OH-]
sodium hydroxide
OCC1CO1
glycidol
O=C(O)C=Cc1ccc(O)cc1
p-hydroxy cinnamic acid
Cl
hydrochloric acid

Reagenzien

Keine

Lösungsmittel

CS(C)=O
DMSO
OCC(O)CO
glycerin

Reaktionsbedingungen

Temperatur
90°CELSIUS
Detaillierte Bedingungen
See reaction.notes.procedure_details.

Aufarbeitung

  1. 1
    Temperaturheating

Vorschrift

1.74 g of p-hydroxy cinnamic acid and 4.0 g of glycidol were dissolved in 2 ml of DMSO, and catalytic amount of hydrochloric acid was added. The solution was heated to 90° C., heating and agitation were carried out for 1 hour, neutralized by adding sodium hydroxide and then the adduct of cinnamic acid and glycerin was obtained.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US05426210uspto-grants-1995_06