Reaktion #50367

ord-9fd1cb87e984445880ac895829b5f575

Reaktionsgleichung

[Na+].[OH-]
sodium hydroxide
O=C(O)C=Cc1ccc(O)cc1
p-hydroxy cinnamic acid
OCC1CO1
glycidol
O=S(=O)(O)O
sulfuric acid
→
O=C(O)C=Cc1ccccc1
cinnamic acid

Edukte

[Na+].[OH-]
sodium hydroxide
O=C(O)C=Cc1ccc(O)cc1
p-hydroxy cinnamic acid
OCC1CO1
glycidol
O=S(=O)(O)O
sulfuric acid

Reagenzien

Keine

Lösungsmittel

CS(C)=O
DMSO
OCC(O)CO
glycerin

Reaktionsbedingungen

Temperatur
90°CELSIUS
Detaillierte Bedingungen
See reaction.notes.procedure_details.

Aufarbeitung

  1. 1
    Temperaturheating

Vorschrift

17.4 g of p-hydroxy cinnamic acid and 40.0 g of glycidol were dissolved in 20 ml of DMSO, and catalytic amount of sulfuric acid was added. The solution was heated to 90° C. and then heating and agitation was carried out for 3 hours, neutralized by adding sodium hydroxide and then adduct of cinnamic acid and glycerin was obtained.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US05426210uspto-grants-1995_06