Reaktion #50278

ord-d03adcd1c58a4cf4849e2f47f02abb57

Reaktionsgleichung

Nc1cc[nH]c(=O)n1
Cytosine
O=S(=O)([O-])[O-].[NH4+].[NH4+]
ammonium sulfate
C[Si](C)(C)N[Si](C)(C)C
hexamethyldisilazane
→
C[Si](C)(C)N(c1cc[nH]c(=O)n1)[Si](C)(C)C
titled product
C[Si](C)(C)N(c1cc[nH]c(=O)n1)[Si](C)(C)C
Bis-trimethylsilylcytosine

Edukte

Nc1cc[nH]c(=O)n1
Cytosine
O=S(=O)([O-])[O-].[NH4+].[NH4+]
ammonium sulfate
C[Si](C)(C)N[Si](C)(C)C
hexamethyldisilazane

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Aufarbeitung

  1. 1
    Sonstigeto form a homogenous solution
  2. 2
    SonstigeThe hexamethyldisilazane was removed by distillation

Vorschrift

Cytosine (12.0 g), hexamethyldisilazane (60 ml) and ammonium sulfate (10 mg) were refluxed at 125° C. for 30 minutes to form a homogenous solution. The hexamethyldisilazane was removed by distillation to form the titled product.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US05426183uspto-grants-1995_06