Reaktion #502319

ord-68cbbc39ef854dfc8bdd95a5c69e7318

Reaktionsgleichung

Nc1c(O)cccc1C(=O)O
3-hydroxyanthranilic acid
CC1(C(=O)Cl)CCCN1C(=O)OCc1ccccc1
benzyl 2-(chlorocarbonyl)-2-methylpyrrolidine-1-carboxylate
→
CC1(c2nc3c(C(=O)O)cccc3o2)CCCN1C(=O)OCc1ccccc1
2-(1-(Benzyloxycarbonyl)-2-methylpyrrolidin-2-yl)benzo[d]oxazole-4-carboxylic acid

Edukte

Nc1c(O)cccc1C(=O)O
3-hydroxyanthranilic acid
CC1(C(=O)Cl)CCCN1C(=O)OCc1ccccc1
benzyl 2-(chlorocarbonyl)-2-methylpyrrolidine-1-carboxylate

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

2-(1-(Benzyloxycarbonyl)-2-methylpyrrolidin-2-yl)benzo[d]oxazole-4-carboxylic acid is prepared from 3-hydroxyanthranilic acid and benzyl 2-(chlorocarbonyl)-2-methylpyrrolidine-1-carboxylate using the conditions described in Example 3A. MS (ESI) m/e 381 [M+H]+.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US08088760B2uspto-grants-2012_01