Reaktion #50215

ord-06d6616fa021449d8371a1195c42430b

Reaktionsgleichung

Brc1ccccn1
2-bromopyridine
CCCc1nn(C)c2c(=O)[nH]c(-c3cc(Br)ccc3OCC)nc12
5-(5-bromo-2-ethoxyphenyl)-1-methyl-3-n-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one
CCCc1nn(C)c2c(=O)[nH]c(-c3cc(-c4ccccn4)ccc3OCC)nc12
title compound
CCCc1nn(C)c2c(=O)[nH]c(-c3cc(-c4ccccn4)ccc3OCC)nc12
2-Ethoxy-5-(2-pyridyl)phenyl-1-methyl-3-n-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

The title compound was prepared from 2-bromopyridine and 5-(5-bromo-2-ethoxyphenyl)-1-methyl-3-n-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one, following the procedure described in Example 32, and was obtained as an off-white solid (33%), m.p. 216°-218° C. Found: C,67.71; H,5.81; N,17.63. C22H23N5O2 requires C,67.85; H,5.95; N,17.98%.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US05426107uspto-grants-1995_06