Reaktion #5021

Reaktionsgleichung

1,7,7-Trimethylbicyclo[2.2.1]heptan-2-one

methyllithium

→

title compound

1,7,7-Trimethylbicyclo[2.2.1]hept-2-ene

Lösungsmittel

ether

Reaktionsbedingungen

Vorschrift

1,7,7-Trimethylbicyclo[2.2.1]heptan-2-one (1-camphor) was converted into its 4-toluenesulfonylhydrazone, which was then reacted with methyllithium in ether, to give the title compound. The method used was that described by Shapiro and Duncan, Organic Synthesis, Vol 51, pp 67-69, for the conversion of racemic camphor into racemic 1,7,7-trimethylbicyclo[2.2.1]hept-2-ene.

Quelle