Reaktion #49946

ord-47782f9b5f06407a89236f994f00b2a5

Reaktionsgleichung

CC(C)(C)N(N)C(=O)c1ccccc1
N'-t-butyl-N'-benzoylhydrazine
O=S(=O)(Cl)c1ccccc1
Benzenesulfonyl chloride
→
CC(C)(C)N(NS(=O)(=O)c1ccccc1)C(=O)c1ccccc1
N'-t-butyl-N-benzenesulfonyl-N'-benzoylhydrazine

Edukte

CC(C)(C)N(N)C(=O)c1ccccc1
N'-t-butyl-N'-benzoylhydrazine
O=S(=O)(Cl)c1ccccc1
Benzenesulfonyl chloride

Reagenzien

Keine

Lösungsmittel

CCOCC
diethyl ether
c1ccncc1
pyridine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Aufarbeitung

  1. 1
    Waschenwashed several times with a 10% HCl solution
  2. 2
    TrocknenThe organic layer was dried over magnesium sulfate
  3. 3
    Filtrationfiltered
  4. 4
    Sonstigeto afford a white solid in good yield

Vorschrift

N'-t-butyl-N'-benzoylhydrazine (0.4 g) was stirred in pyridine (3 ml) at room temperature. Benzenesulfonyl chloride (0.5 g) was added slowly, dropwise and stirred for 2 hours, diluted with diethyl ether (20 ml) and washed several times with a 10% HCl solution and then water. The organic layer was dried over magnesium sulfate, filtered and the solvent rotavapped off to afford a white solid in good yield.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US05424333uspto-grants-1995_06