Reaktion #49945

Reaktionsgleichung

N'-t-butyl-N-benzoylhydrazine

sodium hydroxide

Phenylacetylchloride

→

N'-t-butyl-N-benzoyl-N'-phenylacetylhydrazine

Ausbeute 90.0%

Lösungsmittel

toluene

hexane

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigeat 5° C
2. 2
   Filtrationfiltered off
3. 3
   Sonstigeto yield a solid product
4. 4
   WaschenThe filter cake was washed with hexane and water
5. 5
   Sonstigeto air dry
6. 6
   SonstigeThe white solid product obtained in 90% yield melted at 167°-169° C.

Vorschrift

N'-t-butyl-N-benzoylhydrazine (2 g) was stirred in toluene (35 ml) and 50% aqueous sodium hydroxide (1 g) at 5° C. Phenylacetylchloride (1.5 g) was added slowly, dropwise to the reaction mixture, warmed to room temperature and stirred 1 hour. The reaction mixture was diluted with hexane (50 ml) and filtered off to yield a solid product. The filter cake was washed with hexane and water and allowed to air dry. The white solid product obtained in 90% yield melted at 167°-169° C.

Quelle