Reaktion #49941

Reaktionsgleichung

N'-t-butyl-N-benzoylhydrazine

potassium carbonate

bromoethyl acetate

→

product

Ausbeute 9.4%

N-benzoyl-N'-t-butyl-N'-(ethoxycarbonyl)methylhydrazine

Ausbeute 9.4%

Lösungsmittel

water

ether

dimethylformamide

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigethe organic layer was separated
2. 2
   WaschenThe organic layer was washed several times with water
3. 3
   Trocknendried over magnesium sulfate
4. 4
   Sonstigeto afford an oil
5. 5
   SonstigeChromatographic purification

Vorschrift

N'-t-butyl-N-benzoylhydrazine (2.0 g), powdered potassium carbonate (5 g) and bromoethyl acetate (1.6 g) were stirred in dimethylformamide (20 ml) at 60° C. for 14 hours. The reaction mixture was diluted with water and ether, and the organic layer was separated. The organic layer was washed several times with water, dried over magnesium sulfate and rotavapped to afford an oil. Chromatographic purification gave the pure oil product (0.25 g).

Quelle