Reaktion #49908

Reaktionsgleichung

N'-t-butyl-N,N'-dibenzoylhydrazine

Methoxymethyl chloride

→

N-methoxymethyl-N'-t-butyl-N,N'-dibenzoylhydrazine

Lösungsmittel

toluene

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeThe layers were separated
2. 2
   Waschenthe toluene layer was washed several times with water (until the water washes
3. 3
   TrocknenThe toluene solution was dried over anhydrous magnesium sulfate
4. 4
   Sonstigethe toluene removed under vacuum

Vorschrift

N'-t-butyl-N,N'-dibenzoylhydrazine (2 g, 0.007M) was stirred at room temperature in a two phase system of toluene-50% sodium hydroxide with 100 mg of phase transfer catalyst (tetra-n-butylammonium hydrogen sulfate). Methoxymethyl chloride (1.2 g, 0.015M) was added dropwise and the mixture was stirred 3 hours. The layers were separated and the toluene layer was washed several times with water (until the water washes were neutral). The toluene solution was dried over anhydrous magnesium sulfate and the toluene removed under vacuum to afford N-methoxymethyl-N'-t-butyl-N,N'-dibenzoylhydrazine as a thick oil.

Quelle