Reaktion #499068

Reaktionsgleichung

dimethyl acetonedicarboxylate

→

methyl 2,2,4,4-tetramethyl-3,5-dioxohexanecarboxylate

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigedimethyl tetra-C-methylacetonedicarboxylate was obtained by methylation

Vorschrift

Starting from dimethyl acetonedicarboxylate, dimethyl tetra-C-methylacetonedicarboxylate was obtained by methylation, and this was converted into the dicarboxylic acid methyl ester chloride and then methylated with dimethylcadmium. The methyl 2,2,4,4-tetramethyl-3,5-dioxohexanecarboxylate obtained was cyclized in the presence of sodium methanolate. The total yield (based on dimethyl acetonedicarboxylate) is 0.01% (Chem. Ber. 92, 2033 (1959)).

Quelle