Reaktion #49728

Reaktionsgleichung

2-fluoro-4-methylsulphonylbenzoic acid

thionyl chloride

→

2-fluoro-4-methylsulphonylbenzoyl chloride

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturheated
2. 2
   Temperaturat reflux for 2 hours
3. 3
   TemperaturThe mixture was cooled
4. 4
   Sonstigeevaporated to dryness
5. 5
   workup.ADDITIONToluene was added
6. 6
   Sonstigethe solvent re-evaporated

Vorschrift

A mixture of 2-fluoro-4-methylsulphonylbenzoic acid (6.0 g) and thionyl chloride were stirred and heated at reflux for 2 hours. The mixture was cooled and evaporated to dryness. Toluene was added and the solvent re-evaporated to give 2-fluoro-4-methylsulphonylbenzoyl chloride (6.5 g) as a brown solid which was not further purified.

Quelle