Reaktion #49711

Reaktionsgleichung

methyl 4-hydroxybenzoate

octadecylbromide

potassium carbonate

→

methyl 4-octadecyloxybenzoate

Ausbeute 45.4%

Lösungsmittel

2-butanone

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturwas heated
2. 2
   Temperaturat reflux for 16 hours
3. 3
   SonstigeThe solvent was then removed until 125 ml of 2-butanone
4. 4
   Sonstigehad been collected
5. 5
   TemperaturWhile it was still warm
6. 6
   workup.ADDITIONthe remaining material was poured into methanol (400 ml)
7. 7
   FiltrationThe product was filtered
8. 8
   Sonstigerecrystallized from 2000 ml of methanol

Vorschrift

A mixture containing methyl 4-hydroxybenzoate (45.6 g), octadecylbromide (100 g), and potassium carbonate (41.4 g) in 2-butanone (200 ml) was heated at reflux for 16 hours. The solvent was then removed until 125 ml of 2-butanone had been collected. While it was still warm, the remaining material was poured into methanol (400 ml). The product was filtered and recrystallized from 2000 ml of methanol to give methyl 4-octadecyloxybenzoate (55 g).

Quelle