Reaktion #493595

Reaktionsgleichung

2-amino-4-methoxy-3-methyl benzamide

benzamide

3,5-difluoro-benzoyl chloride

→

title compound

Ausbeute 85.0%

2-(3,5-Difluoro-phenyl)-7-methoxy-8-methyl-quinazolin-4-ol

Ausbeute 85.0%

Reaktionsbedingungen

Vorschrift

The general procedure described in Example 10 was followed using 2-amino-4-methoxy-3-methyl benzamide as benzamide derivative [A] and 3,5-difluoro-benzoyl chloride as acid chloride [B], which gave the title compound (2.1 g, 85%), [M+H]=303.

Quelle