Reaktion #493185

Reaktionsgleichung

water

tert-butyl-chloro-dimethyl-silane

imidazole

3-benzyloxy-phenol

→

(3-Benzyloxy-phenoxy)-tert-butyl-dimethyl-silane

Lösungsmittel

THF

Reaktionsbedingungen

Aufarbeitung

1. 1
   Extraktionthe mixture was then extracted with methylene chloride
2. 2
   ExtraktionThe organic phase was extracted three times with water
3. 3
   Trocknendried over sodium sulfate
4. 4
   Einengenconcentrated in vacuo
5. 5
   Filtrationfiltered over Alox (neutral)
6. 6
   Einengenconcentrated

Vorschrift

43.459 ml tert-butyl-chloro-dimethyl-silane were added at rt to a solution of 17 g imidazole and 25 g 3-benzyloxy-phenol in 400 ml THF. After 3 hours water was added to the reaction mixture and the mixture was then extracted with methylene chloride. The organic phase was extracted three times with water, dried over sodium sulfate and concentrated in vacuo. The residue was solved in methylene chloride and filtered over Alox (neutral) and concentrated.

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