Reaktion #490328

Reaktionsgleichung

dibenzo[b,d]furan-4-yl boronic acid

bis(3-bromo-phenyl)diphenylsilane

K2CO3

→

(3-bromophenyl)(3-(dibenzo[b,d]furan-4-yl)phenyl)diphenylsilane

Ausbeute 64.2%

Lösungsmittel

toluene

water

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigethe organic phase was separated
2. 2
   Sonstigeevaporated to dryness
3. 3
   SonstigeThe residue was purified by column chromatography on silica gel with hexane:DCM (9.5:0.5

Vorschrift

A mixture solution of dibenzo[b,d]furan-4-yl boronic acid (2.5 g, 11.79 mmol), bis(3-bromo-phenyl)diphenylsilane (14.57 g, 29.5 mmol), Pd(PPh3)4 (0.136 g, 0.118 mmol) and K2CO3 (3.26 g, 23.58 mmol) in 150 mL of toluene and 50 mL water was refluxed under nitrogen overnight. After cooling to room temperature, the organic phase was separated and evaporated to dryness. The residue was purified by column chromatography on silica gel with hexane:DCM (9.5:0.5, v/v) as eluent to yield (3-bromophenyl)(3-(dibenzo[b,d]furan-4-yl)phenyl)diphenylsilane (4.4 g, 64%) as a white solid.

Quelle