Reaktion #489991

Reaktionsgleichung

6-bromo-8-chloro-4,4-dimethyl-3,4-dihydro-2H-thiochromene

n-BuLi

DMF

→

desired product

8-chloro-4,4-dimethyl-3,4-dihydro-2H-thiochromene-6-carbaldehyde

Reaktionsbedingungen

Vorschrift

Using essentially the same procedure as Example 5-20, Step 3, 6-bromo-8-chloro-4,4-dimethyl-3,4-dihydro-2H-thiochromene (954 mg, 3.27 mmol), n-BuLi (1.57 mL, 3.93 mmol) and DMF (1.01 mL, 13.1 mmol) afforded the desired product as a pale-yellow oil.

Quelle