Reaktion #4885

Reaktionsgleichung

ammonia

8-Hydroxy-2-methyl-7-quinolinecarboxylic acid methyl ester

ammonia

→

title compound

8-Hydroxy-2-methyl-7-quinolinecarboxamide

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigeto evaporate
2. 2
   Sonstigethe residue is crystallized from a suitable solvent

Vorschrift

8-Hydroxy-2-methyl-7-quinolinecarboxylic acid methyl ester is reacted with excess ammonia in a steel bomb for 12-18 hr. The excess ammonia is allowed to evaporate and the residue is crystallized from a suitable solvent to give the title compound.

Quelle