Reaktion #487557

Reaktionsgleichung

lead tetraacetate

4′-chloro-4-ethylbiphen-3-ylboronic acid

→

4′-chloro-4-ethylbiphen-3-yllead triacetate

Ausbeute 100.0%

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigethoroughly flushed with nitrogen
2. 2
   workup.ADDITIONis added anhydrous chloroform (6 ml)
3. 3
   Temperaturthe suspension is heated at this temperature for 5 hours
4. 4
   TemperaturThe mixture is then cooled to room temperature
5. 5
   Einengenconcentrated to a small volume
6. 6
   Sonstigetriturated with hexanes
7. 7
   Filtrationfiltered

Vorschrift

To a mixture of lead tetraacetate (2.15 g, 4.85 mmol) and mercuric diacetate (0.15 g, 0.47 mmol), thoroughly flushed with nitrogen, is added anhydrous chloroform (6 ml). This mixture is warmed to 40° C., and 4′-chloro-4-ethylbiphen-3-ylboronic acid (1.17 g, 4.50 mmol) is added in one portion and the suspension is heated at this temperature for 5 hours. The mixture is then cooled to room temperature, concentrated to a small volume and triturated with hexanes and filtered to yield crude 4′-chloro-4-ethylbiphen-3-yllead triacetate (2.70 g).

Quelle