Reaktion #487521

Reaktionsgleichung

6-Methoxy-naphthaldehyde

THF

→

6-methoxy-2-vinyl-naphthalene

Ausbeute 90.0%

Lösungsmittel

ether

Reaktionsbedingungen

Aufarbeitung

1. 1
   Filtrationis filtered on Celite, and it
2. 2
   Sonstigeis chromatographed (hexane/AcOEt 5:1)

Vorschrift

6-Methoxy-naphthaldehyde (432 mg, 2.35 mmol) is added to a solution of instantaneous ylide (Ph3P+Br−+NaNH2, 1.48 g, 2.4 mmol) in anhydrous THF (5 ml). After one hour of stirring at ambient temperature, it is diluted with ether, it is filtered on Celite, and it is chromatographed (hexane/AcOEt 5:1) to obtain 6-methoxy-2-vinyl-naphthalene (390 mg, 90%).

Quelle