Reaktion #486231

Reaktionsgleichung

1H-indazole-3-carboxylic acid

1,1'-carbonyldiimidazole

4-(2-aminoethyl)morpholine

→

colorless crystals

Ausbeute 24.3%

N-[2-(4-morpholinyl)ethyl]-1H-indazole-3-carboxamide

Ausbeute 24.3%

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeThe ethyl acetate extracts were evaporated to 0.468 g solid
2. 2
   SonstigeCrystallization from ethyl acetate

Vorschrift

Same procedure followed as described in Example 1. The following amounts were used: 1H-indazole-3-carboxylic acid (0.65 g, 4 mmol), 1,1'-carbonyldiimidazole (0.65 g, 4 mmol) and 4-(2-aminoethyl)morpholine (0.52 mL, 4 mmol). The ethyl acetate extracts were evaporated to 0.468 g solid. Crystallization from ethyl acetate provided 0.267 g colorless crystals. Mass spectrum, m+ =274.

Quelle