Reaktion #485907
ord-bf4e855ddde84503a7f4c7bcf902b01c
Reaktionsgleichung
8-hydroxyquinoline
formaldehyde
γ-aminopropyltriethoxysilane
trimethylchlorosilane
nitrobenzene
hydrochloric acid
→
hydroxyquinoline
Edukte
Reagenzien
Keine
Lösungsmittel
Reaktionsbedingungen
Detaillierte Bedingungen
See reaction.notes.procedure_details.
Vorschrift
Preferably, Route A can be used. A chloromethylated ligand can be prepared, for example, by reacting 8-hydroxyquinoline with formaldehyde and hydrochloric acid. That derivative is further reacted with γ-aminopropyltriethoxysilane in the presence of trimethylchlorosilane and triethylamine and nitrobenzene. Next, the prepared organosilicon derivative is reacted with the support to obtain hydroxyquinoline modified silica gel. A sample of this sequence of reactions is described in further detail in Example 2 below.