Reaktion #482947

ord-e7ce18e7afec4d89a247f404b5714295

Reaktionsgleichung

CC(C)(C)c1ccc(C(=O)Cl)cc1
4-tert-butylbenzoyl chloride
Nc1cc([N+](=O)[O-])ccc1C(=O)Nc1cccc(OCc2ccccc2)c1
2-amino-N-(3-benzyloxyphenyl)-4-nitrobenzamide
→
CC(C)(C)c1ccc(C(=O)Nc2cc([N+](=O)[O-])ccc2C(=O)Nc2cccc(OCc3ccccc3)c2)cc1
title product
Ausbeute 69.0%
CC(C)(C)c1ccc(C(=O)Nc2cc([N+](=O)[O-])ccc2C(=O)Nc2cccc(OCc3ccccc3)c2)cc1
N-(3-Benzyloxyphenyl)-2-[(4-tert-butylbenzoyl)amino]-4-nitrobenzamide
Ausbeute 69.0%

Edukte

CC(C)(C)c1ccc(C(=O)Cl)cc1
4-tert-butylbenzoyl chloride
Nc1cc([N+](=O)[O-])ccc1C(=O)Nc1cccc(OCc2ccccc2)c1
2-amino-N-(3-benzyloxyphenyl)-4-nitrobenzamide

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

Using the procedure described in Example 93, Part A, 4-tert-butylbenzoyl chloride (3.5 mmol) and 2-amino-N-(3-benzyloxyphenyl)-4-nitrobenzamide (3.2 mmol) yielded 0.69 g (69%) of the title product.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US06605626B2uspto-grants-2003_08