Reaktion #482611

ord-5c82a2d9956947a48333765e37336b52

Reaktionsgleichung

Cl.O.O=C1CCNCC1
4-Piperidone hydrochloride monohydrate
COc1cc(-c2cc(CCl)ccn2)cc(OC)c1OC
4-chloromethyl-2-(3,4,5-trimethoxyphenyl)pyridine
COc1cc(-c2cc(CN3CCC(=O)CC3)ccn2)cc(OC)c1OC
title compound
COc1cc(-c2cc(CN3CCC(=O)CC3)ccn2)cc(OC)c1OC
1-[[2-(3,4,5-Trimethoxyphenyl)pyridin-4-yl]methyl]-4-piperidone

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

4-Piperidone hydrochloride monohydrate (3.07 g) and 4-chloromethyl-2-(3,4,5-trimethoxyphenyl)pyridine (2.94 g) were coupled by the same manner as described in Example 2 to give the title compound.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US06605620B1uspto-grants-2003_08