Reaktion #48147
ord-2e61059cfd6d4154b127a196e0f3dd59
Reaktionsgleichung
[5-(1-isopropyl-piperidin-4-yloxy)-1H-indol-2-yl]-morpholin-4-yl-methanone
intermediate 2
[5-(1-isopropyl-piperidin-4-yloxy)-1H-indol-2-yl]-morpholin-4-yl-methanone
4-methylbenzeneboronic acid
→
title compound
[5-(1-Isopropyl-piperidin-4-yloxy)-1-p-tolyl-1H-indol-2-yl]-morpholin-4-yl-methanone
Edukte
Reagenzien
Keine
Reaktionsbedingungen
Detaillierte Bedingungen
See reaction.notes.procedure_details.
Aufarbeitung
- 1SonstigeIn analogy to the procedure described for the synthesis of example 6
Vorschrift
In analogy to the procedure described for the synthesis of example 6, the title compound was synthesized from [5-(1-isopropyl-piperidin-4-yloxy)-1H-indol-2-yl]-morpholin-4-yl-methanone (intermediate 2) and 4-methylbenzeneboronic acid. The title compound was obtained in 57% yield as a yellow foam. MS (m/e): 462.2 (MH+, 100%).