Reaktion #480562

Reaktionsgleichung

N-(3,5-bis-trifluoro-methylbenzyl)-N-methyl-6-morpholin-4-yl-4-o-tolyl-nicotinamide

N-(3,5-Bis-trifluoromethyl-benzyl)-N-methyl-6-morpholin-4-yl-4-o-tolyl-nicotinamide

1-chloromethyl-2-methylnaphthalene

→

N-Methyl-N-(2-methyl-naphthalen-1-ylmethyl)-6-morpholin-4-yl-4-o-tolyl-nicotinamide

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeThe parent compound was obtained as a white solid
2. 2
   Sonstigein comparable yield

Vorschrift

The parent compound was obtained as a white solid in comparable yield according to the procedure described above for the preparation of N-(3,5-bis-trifluoro-methylbenzyl)-N-methyl-6-morpholin-4-yl-4-o-tolyl-nicotinamide (Example 16, step d) using 1-chloromethyl-2-methylnaphthalene instead of 3,5-bis-trifluoromethyl-benzyl bromide.

Quelle