Reaktion #479738

Reaktionsgleichung

hydrochloric acid

4-chloro-2-nitroaniline

Sodium nitrite

→

4-Chloro-2-nitrobenzenediazonium Chloride

Lösungsmittel

water

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeTo a 500 mL three-necked flask fitted with a mechanical stirrer
2. 2
   Sonstigeis reduced to 0° C
3. 3
   Temperaturwhile maintaining the solution at 0° C
4. 4
   FiltrationThe diazonium salt solution (281 g) is then filtered
5. 5
   Sonstigestored at −15° C. until later use

Vorschrift

To a 500 mL three-necked flask fitted with a mechanical stirrer are added 134.2 g of concentrated hydrochloric acid and 60 g of 4-chloro-2-nitroaniline. After heating to 65° C., 106.6 g of water is added at which time the temperature is reduced to 0° C. Sodium nitrite (63.4 g, 40 wt %) is slowly added to the slurry while maintaining the solution at 0° C. The diazonium salt solution (281 g) is then filtered and stored at −15° C. until later use.

Quelle