Reaktion #47923

Reaktionsgleichung

1-(3,3-dimethyl-6-nitroindolin-1-yl)ethanone

→

solid

Ausbeute 99.4%

1-(6-amino-3,3-dimethylindolin-1-yl)ethanone

Ausbeute 99.4%

Lösungsmittel

EtOH

Reaktionsbedingungen

Aufarbeitung

1. 1
   FiltrationThe catalyst was filtered out
2. 2
   Einengenthe filtrate was concentrated

Vorschrift

A mixture of 1-(3,3-dimethyl-6-nitroindolin-1-yl)ethanone (300 mg), 10% Pd—C (50 mg), and EtOH (50 mL) was stirred under hydrogen atmosphere (1 atm) for 3 h. The catalyst was filtered out and the filtrate was concentrated to give a light yellow solid (260 mg).

Quelle