Reaktion #47725

Reaktionsgleichung

N2,4-dip-tolylpyridine-2,3-diamine

2-(ethoxymethylene)malonnitrile

→

3,7-dip-tolyl-3H-imidazo[4,5-b]pyridine

Ausbeute 84.0%

Lösungsmittel

isopropanol

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturrefluxed for 6 hours
2. 2
   SonstigeThe solution was removed
3. 3
   Sonstigewas purified
4. 4
   Sonstigeto thereby produce a solid crystalline product at a yield of 84%

Vorschrift

0.70 mol of N2,4-dip-tolylpyridine-2,3-diamine and 2.56 mol of 2-(ethoxymethylene)malonnitrile were added in 10 ml of isopropanol, and refluxed for 6 hours. The solution was removed and was purified by using column chromatography to thereby produce a solid crystalline product at a yield of 84%.

Quelle