Reaktion #473858

ord-6da7edeecbd149378cedbd220c04ad87

Reaktionsgleichung

CC(=O)Nc1ccc2oc(-c3ccc(O)cc3)c(O)c(=O)c2c1
2-(4-hydroxyphenyl)-3-hydroxy-6-acetamido-4H-1-benzopyran-4-one
→
CC(=O)Nc1ccc2oc(-c3ccc(O)cc3)c(OCc3ccccc3)c(=O)c2c1
2-(4-hydroxyphenyl)-3-benzyloxy-6-acetamido-4H-1-benzopyran-4-one
Ausbeute 84.0%

Edukte

CC(=O)Nc1ccc2oc(-c3ccc(O)cc3)c(O)c(=O)c2c1
2-(4-hydroxyphenyl)-3-hydroxy-6-acetamido-4H-1-benzopyran-4-one

Reagenzien

Keine

Lösungsmittel

CO.ClC(Cl)Cl
Chloroform Methanol

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Aufarbeitung

  1. 1
    SonstigePrepared analogously to Example 5d

Vorschrift

Prepared analogously to Example 5d, starting from 2-(4-hydroxyphenyl)-3-hydroxy-6-acetamido-4H-1-benzopyran-4-one. Yield: 84%; Rf (9/1 Chloroform/Methanol): 0.59, 1H-NMR (d6-DMSO): 10.38 (s broad, 1H), 8.40 (d, 1H), 8.1-7.9 (m, 3H), 7.70 (d, 1H); 7.55-7.25 (m, 10H); 7.17 (d, 2H); 5.22 (s, 2H), 5.07 (s, 2H); 2.11 (s, 3H).

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US08372866B2uspto-grants-2013_02