Reaktion #470387

Reaktionsgleichung

N1-phenylbenzene-1,2-diamine

benzaldehyde

→

desired product

Ausbeute 37.0%

1,2-diphenyl-1H-benzo[d]imidazole

Ausbeute 37.0%

Lösungsmittel

methoxylethanol

Reaktionsbedingungen

Aufarbeitung

1. 1
   TemperaturThe mixture was heated up
2. 2
   Temperaturto reflux for 48 hours
3. 3
   Sonstigethe solvent was evaporated
4. 4
   SonstigeThe residue was purified by column chromatography

Vorschrift

N1-phenylbenzene-1,2-diamine (4.15 g, 22 mmol) and benzaldehyde (2.1 g, 20 mmol) were mixed with methoxylethanol (60 ml) in a three-neck flask. The mixture was heated up to reflux for 48 hours. After cooled to room temperature, the solvent was evaporated. The residue was purified by column chromatography using dichloromethane to 5% of ethyl acetate in dichloromethane as eluent. 2 g of desired product was obtained.

Quelle