Reaktion #470368

Reaktionsgleichung

sodium acetate

N-methoxymethyl-N-methylpyrrolidinium chloride

N-Methyl-N-Methoxymethylpyrrolidinium Chloride

→

desired product

N-Methoxymethyl-N-Methylpyrrolidinium Acetate

Lösungsmittel

methanol

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeThe mixture was reacted at room temperature for 1.5 hours
2. 2
   Sonstigewhereby the reaction was terminated
3. 3
   FiltrationThe reaction mixture was filtered
4. 4
   Einengenthe filtrate was concentrated
5. 5
   Sonstigedried in a vacuum
6. 6
   workup.ADDITIONTo the residue was added 100 ml of dichloromethane
7. 7
   Filtrationfollowed by filtration with a membrane
8. 8
   Filtrationfilter
9. 9
   Einengenconcentration in a vacuum
10. 10
    Sonstigedrying

Vorschrift

A 9.46 g quantity of sodium acetate (product of Wako Pure Chemical Ind. Ltd.) was dissolved in 95 g of methanol, and 19.10 g of N-methoxymethyl-N-methylpyrrolidinium chloride was added to the solution. The mixture was reacted at room temperature for 1.5 hours, whereby the reaction was terminated. The reaction mixture was filtered, and the filtrate was concentrated and dried in a vacuum. To the residue was added 100 ml of dichloromethane, followed by filtration with a membrane filter, concentration in a vacuum and drying, affording 20.38 g of the desired product.

Quelle