Reaktion #470364

Reaktionsgleichung

sodium carbonate

N-methoxymethyl-N-methylpyrrolidinium chloride

N-Methyl-N-Methoxymethylpyrrolidinium Chloride

→

desired product

N-Methoxymethyl-N-Methylpyrrolidinium Carbonate

Lösungsmittel

water

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeThe mixture was reacted at room temperature for 0.5 hour
2. 2
   Sonstigewhereby the reaction was terminated
3. 3
   EinengenThe reaction mixture was concentrated
4. 4
   Trocknendried in vacuum, and 100 ml of ethyl alcohol
5. 5
   workup.ADDITIONwas added to the residue
6. 6
   Sonstigeto remove insoluble sodium chloride
7. 7
   workup.DISSOLUTIONThe resulting product was dissolved in dichloromethane
8. 8
   Filtrationthe solution was filtered with a membrane
9. 9
   Filtrationfilter again
10. 10
    Einengenthe filtrate was concentrated in a vacuum
11. 11
    Sonstigedried

Vorschrift

A 1.60 g quantity of sodium carbonate (product of Wako Pure Chemical Ind. Ltd.) was dissolved in 18 g of deionized water, and 5.01 g of N-methoxymethyl-N-methylpyrrolidinium chloride was added to the solution. The mixture was reacted at room temperature for 0.5 hour, whereby the reaction was terminated. The reaction mixture was concentrated and dried in vacuum, and 100 ml of ethyl alcohol was added to the residue to remove insoluble sodium chloride. The resulting product was dissolved in dichloromethane, the solution was filtered with a membrane filter again, and the filtrate was concentrated in a vacuum and dried, giving 5.41 g of the desired product.

Quelle