Reaktion #46999

Reaktionsgleichung

cis-4,5-bis-(4-chlorophenyl)imidazolidine-2-thione

cis-4,5-bis-(4-Chlorophenyl)imidazolidine-2-thione

methyl iodide

→

product 51

Ausbeute 75.3%

cis-4,5-bis-(4-Chlorophenyl)-2-methylthio-4,5-dihydro-1H-imidazole hydroiodide

Ausbeute 75.3%

Lösungsmittel

EtOH

Reaktionsbedingungen

Aufarbeitung

1. 1
   Einengenconcentrated in vacuo
2. 2
   Sonstigethe residue triturated with abs EtOH
3. 3
   FiltrationThe insoluble material is filtered

Vorschrift

A mixture of cis-4,5-bis-(4-chlorophenyl)imidazolidine-2-thione (34) (30 g, 0.0928 mol) and methyl iodide (11.5 mL, 0.186 mol) in abs. EtOH (100 mL) is heated at 90° C. for 8 h. The reaction mixture is cooled to rt, concentrated in vacuo, and the residue triturated with abs EtOH. The insoluble material is filtered to give 32.5 g of the product 51.

Quelle