Reaktion #46997

Reaktionsgleichung

cis-4,5-bis-(2-chlorophenyl)imidazolidine-2-thione

cis-4,5-bis-(2-Chlorophenyl)imidazolidine-2-thione

methyl iodide

→

product 49

Ausbeute 75.8%

cis-4,5-bis-(2-Chlorophenyl)-2-methylthio-4,5-dihydro-1H-imidazole hydroiodide

Ausbeute 75.8%

Lösungsmittel

EtOH

Reaktionsbedingungen

Aufarbeitung

1. 1
   Einengenconcentrated in vacuo
2. 2
   FiltrationThe insoluble material is filtered

Vorschrift

A mixture of cis-4,5-bis-(2-chlorophenyl)imidazolidine-2-thione (32) (10.1 g, 0.0312 mol) and methyl iodide (3.89 mL, 0.0624 mol) in abs. EtOH (15 mL) is heated at 90° C. for 6 h. The reaction mixture is cooled to rt, concentrated in vacuo, and the residue suspended in abs EtOH. The insoluble material is filtered to give 11 g of the product 49.

Quelle