Reaktion #46926

ord-55d07d2dbfdb47ff89085fd991994fa3

Reaktionsgleichung

O=Cc1ccc(Br)cc1
4-Bromobenzaldehyde
C=CC(C)=O
but-3-en-2-one
Nc1ccc(S(N)(=O)=O)cc1
p-aminosulfonyl phenylamine
→
Cc1ccc(-c2ccc(Br)cc2)n1-c1ccc(S(N)(=O)=O)cc1
titled compound
Cc1ccc(-c2ccc(Br)cc2)n1-c1ccc(S(N)(=O)=O)cc1
4-[2-(4-bromo-phenyl)-5-methyl-pyrrol-1-yl]-benzenesulfonamide

Edukte

O=Cc1ccc(Br)cc1
4-Bromobenzaldehyde
C=CC(C)=O
but-3-en-2-one
Nc1ccc(S(N)(=O)=O)cc1
p-aminosulfonyl phenylamine

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

4-Bromobenzaldehyde and but-3-en-2-one were treated according to the procedure outlined in General Procedure C followed by subjecting the resulting product to conditions outlined in General Procedure D along with p-aminosulfonyl phenylamine to obtain the titled compound. 1H NMR (CDCl3) δ ppm 2.15 (3H), 4.81 (2H), 6.15 (1H), 6.29 (1H), 6.95-7.85 (8H); MS (ESI) m/z 391/393 (M+H)

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US07741364B2uspto-grants-2010_06