Reaktion #467450

Reaktionsgleichung

1,3-dihydroxyadamantane

acetic acid-acetic anhydride

hydroxyadamantane

→

1,3,5-trihydroxyadamantane

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturwith heating
2. 2
   Sonstigethe reaction for 8 hours
3. 3
   Sonstigeto obtain
4. 4
   SonstigeThis mixture was partitioned by high performance liquid chromatography

Vorschrift

One mol of 1,3-dihydroxyadamantane was stirred in an acetic acid-acetic anhydride solution of CrO3, oxidizing agent, with heating. After carrying out the reaction for 8 hours, the reaction solution was neutralized to obtain a mixture of polyhydroxylated compounds of hydroxyadamantane. This mixture was partitioned by high performance liquid chromatography to obtain 1,3,5-trihydroxyadamantane.

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