Reaktion #46713

ord-92d8d03154da4df1bf9554108293e953

Reaktionsgleichung

CC(C)S(=O)(=O)NC1Cc2ccc(I)cc2C1
N-(5-iodo-2,3-dihydro-1H-inden-2-yl)-2-propanesulfonamide
NS(=O)(=O)c1cccc(B(O)O)c1
[3-(aminosulfonyl)phenyl]boronic acid
→
CC(C)S(O)(O)NC1Cc2ccc(-c3cccc(S(N)(=O)=O)c3)cc2C1
title compound
CC(C)S(O)(O)NC1Cc2ccc(-c3cccc(S(N)(=O)=O)c3)cc2C1
3-(2-{[dihydroxy(1-methylethyl)-λ4-sulfanyl]amino}-2,3-dihydro-1H-inden-5-yl)benzenesulfonamide

Edukte

CC(C)S(=O)(=O)NC1Cc2ccc(I)cc2C1
N-(5-iodo-2,3-dihydro-1H-inden-2-yl)-2-propanesulfonamide
NS(=O)(=O)c1cccc(B(O)O)c1
[3-(aminosulfonyl)phenyl]boronic acid

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

The title compound was prepared from N-(5-iodo-2,3-dihydro-1H-inden-2-yl)-2-propanesulfonamide and [3-(aminosulfonyl)phenyl]boronic acid (WO2003004472) in a similar manner to Example 1.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US07741351B2uspto-grants-2010_06