Reaktion #467056

ord-ea3f4c2fb6c943a0a9fdd901e4455fcb

Reaktionsgleichung

CCOC(=O)n1c(C(=O)c2cncnc2)c(N)c2ccc(Cl)cc21
3-amino-6-chloro-1-ethoxycarbonyl-2-(5-pyrimidinylcarbonyl)indole
CCOC(=O)n1c(C(=O)c2cncnc2)c(N)c2ccc(Cl)cc21
3-Amino-6-chloro-1-ethoxycarbonyl-2-(5-pyrimidinylcarbonyl)indole
CC(=O)Cl
acetyl chloride
→
CCOC(=O)n1c(C(=O)c2cncnc2)c(NC(C)=O)c2ccc(Cl)cc21
title compound
CCOC(=O)n1c(C(=O)c2cncnc2)c(NC(C)=O)c2ccc(Cl)cc21
3-Acetylamino-6-chloro-1-ethoxycarbonyl-2-(5-pyrimidinylcarbonyl)indole

Edukte

CCOC(=O)n1c(C(=O)c2cncnc2)c(N)c2ccc(Cl)cc21
3-amino-6-chloro-1-ethoxycarbonyl-2-(5-pyrimidinylcarbonyl)indole
CCOC(=O)n1c(C(=O)c2cncnc2)c(N)c2ccc(Cl)cc21
3-Amino-6-chloro-1-ethoxycarbonyl-2-(5-pyrimidinylcarbonyl)indole
CC(=O)Cl
acetyl chloride

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

The title compound was prepared according to the procedure described in step 1 of Example 2 (Method A) employing 3-amino-6-chloro-1-ethoxycarbonyl-2-(5-pyrimidinylcarbonyl)indole (step 2) and acetyl chloride.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US06300363B1uspto-grants-2001_10