Reaktion #46704

ord-ba8f21bce08e4b7abcf93116021a7f52

Reaktionsgleichung

CC(C)S(=O)(=O)NC1Cc2ccc(B3OC(C)(C)C(C)(C)O3)cc2C1
N-[5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2,3-dihydro-1H-inden-2-yl]-2-propanesulfonamide
CC(=O)Cc1cccc(Br)c1
1-(3-bromophenyl)-2-propanone
→
CC(=O)Cc1cccc(-c2ccc3c(c2)CC(NS(=O)(=O)C(C)C)C3)c1
title compound
CC(=O)Cc1cccc(-c2ccc3c(c2)CC(NS(=O)(=O)C(C)C)C3)c1
N-{5-[3-(2-oxopropyl)phenyl]-2,3-dihydro-1H-inden-2-yl}-2-propanesulfonamide

Edukte

CC(C)S(=O)(=O)NC1Cc2ccc(B3OC(C)(C)C(C)(C)O3)cc2C1
N-[5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2,3-dihydro-1H-inden-2-yl]-2-propanesulfonamide
CC(=O)Cc1cccc(Br)c1
1-(3-bromophenyl)-2-propanone

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

The title compound was prepared from N-[5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2,3-dihydro-1H-inden-2-yl]-2-propanesulfonamide and 1-(3-bromophenyl)-2-propanone in a similar manner to Example 1.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US07741351B2uspto-grants-2010_06