Reaktion #467034

ord-cae24f1856d84b388ef6893563876702

Reaktionsgleichung

CCOC(=O)n1c(C(=O)c2ccccc2)c(NC(C)=O)c2ccc(Cl)cc21
3-acetylamino-2-benzoyl-6-chloro-1-(ethoxycarbonyl)indole
COC(=O)CBr
methyl bromoacetate
→
CCOC(=O)n1c(C(=O)c2ccccc2)c(N(CC(=O)OC)C(C)=O)c2ccc(Cl)cc21
title compound
CCOC(=O)n1c(C(=O)c2ccccc2)c(N(CC(=O)OC)C(C)=O)c2ccc(Cl)cc21
3-(N-Acetyl-N-methoxycarbonylmethylamino)-2-benzoyl-6-chloro-1-(ethoxycarbonyl)indole

Edukte

CCOC(=O)n1c(C(=O)c2ccccc2)c(NC(C)=O)c2ccc(Cl)cc21
3-acetylamino-2-benzoyl-6-chloro-1-(ethoxycarbonyl)indole
COC(=O)CBr
methyl bromoacetate

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

The title compound was prepared according to the procedure described in Example 146 from 3-acetylamino-2-benzoyl-6-chloro-1-(ethoxycarbonyl)indole (Example 2, step 2) and methyl bromoacetate.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US06300363B1uspto-grants-2001_10