Reaktion #467033

ord-272924f3ee8d454e80c335e32b798eb7

Reaktionsgleichung

CCCCCC.CCOC(C)=O
ethyl acetate hexane
CCOC(=O)n1c(C(=O)C2CCCCC2)c(NC(C)=O)c2ccc(Cl)cc21
3-acetylamino-6-chloro-2-cyclohexylcarbonyl-1-(ethoxycarbonyl)indole
CCOC(=O)n1c(C(=O)C2CCCCC2)c(NC(C)=O)c2ccc(Cl)cc21
3-Acetylamino-6-chloro-2-(cyclohexanecarbonyl)-1-(ethoxycarbonyl)indole
→
CC(=O)N(C)c1c(C(=O)C2CCCCC2)[nH]c2cc(Cl)ccc12
title compound
CC(=O)N(C)c1c(C(=O)C2CCCCC2)[nH]c2cc(Cl)ccc12
3-(N-acetyl-N-methylamino)-6-chloro-2-(cyclohexanecarbonyl)indole

Edukte

CCCCCC.CCOC(C)=O
ethyl acetate hexane
CCOC(=O)n1c(C(=O)C2CCCCC2)c(NC(C)=O)c2ccc(Cl)cc21
3-acetylamino-6-chloro-2-cyclohexylcarbonyl-1-(ethoxycarbonyl)indole
CCOC(=O)n1c(C(=O)C2CCCCC2)c(NC(C)=O)c2ccc(Cl)cc21
3-Acetylamino-6-chloro-2-(cyclohexanecarbonyl)-1-(ethoxycarbonyl)indole

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

The title compound was prepared from 3-acetylamino-6-chloro-2-cyclohexylcarbonyl-1-(ethoxycarbonyl)indole (step 1) according to the procedure described in Example 146. m.p.: 162-163° C. (ethyl acetate/hexane)

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US06300363B1uspto-grants-2001_10