Reaktion #467031

ord-0f327e37419b46539a542107c7548fbc

Reaktionsgleichung

CCO.CCOCC
ethanol diethyl ether
CCOC(=O)n1c(C(=O)c2cccc(C)c2)c(NC(C)=O)c2ccc(Cl)cc21
3-acetylamino-6-chloro-1-ethoxycarbonyl-2-(3-methylbenzoyl)indole
→
CC(=O)N(C)c1c(C(=O)c2cccc(C)c2)[nH]c2cc(Cl)ccc12
title compound
CC(=O)N(C)c1c(C(=O)c2cccc(C)c2)[nH]c2cc(Cl)ccc12
3-(N-Acetyl-n-methylamino)-6-chloro-2-(3-methylbenzoyl)indole

Edukte

CCO.CCOCC
ethanol diethyl ether
CCOC(=O)n1c(C(=O)c2cccc(C)c2)c(NC(C)=O)c2ccc(Cl)cc21
3-acetylamino-6-chloro-1-ethoxycarbonyl-2-(3-methylbenzoyl)indole

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

The title compound was prepared from 3-acetylamino-6-chloro-1-ethoxycarbonyl-2-(3-methylbenzoyl)indole (Example 22, step 1) according to the procedure described in Example 146. m.p.: 166-171° C. (ethanol/diethyl ether)

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US06300363B1uspto-grants-2001_10